Current Derivatization Method

CPRIT tool kit Reactions

We have expertise in: Chemo- and Site selective derivatization of complex small molecules (including natural products) and derivatives on microscale for SAR studies; Design, chemical synthesis and scale up of simplified, equipotent derivatives of initial lead compounds; Isolation, purification and structure elucidation of bioactive small molecules and derivatives; Synthesis of Cellular Probes to address cellular localization and cellular target/off-target indetification;  Isolation of putative cellular receptors for bioactive small molecules; and Early preclinical studies.