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The Baylor CPRIT Synthesis and Drug-Lead Discovery Laboratory will focus on the devolpment and application of chemo- and site-selective methods for the derivatization of biologically and pharmacologically important natural products and other bioactive small molecules and the high throughput optimization of synthetic transformations.

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Lab News:

New Publication Accepted: “A Strategy for Dual Inhibition of the Proteasome and Fatty Acid Synthase with Belactosin C-Orlistat Hybrids” Mingzhao Zhu, Wayne D. Harshbarger, Omar Robles, Joanna Krysiak, Kenneth G. Hull, Sung Wook Cho, Robyn D. Richardson, Yanyan Yang, Andres Garcia, Lindsey Spiegelman, Bianca Ramirez, Christopher T. Wilson, Ju Anne Yau, James T. Moore, Caitlen B. Walker, James C. Sacchettini, Wenshe Liu, Stephan A. Sieber, Jeffrey W. Smith and Daniel Romo Bioorg. Med. Chem. (Jan. 2017) DOI: http:// dx.doi.org/10.1016/j.bmc.2017.01.020

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