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The Baylor CPRIT Synthesis and Drug-Lead Discovery Laboratory will focus on the devolpment and application of chemo- and site-selective methods for the derivatization of biologically and pharmacologically important natural products and other bioactive small molecules and the high throughput optimization of synthetic transformations.

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Lab News:

Two New Publications Accepted for Publication:

“Triterpenoids from the stem bark of Vitellaria paradoxa (Sapotaceae) and derived esters exhibit cytotoxicity against a breast cancer cell line” Kenneth O. Eyong, Guerisson Baïrys, Anna A. Eno, Joseph Taube, Kenneth G. Hull, Gabriel N. Folefoc, Harquin S. Foyet, and Daniel Romo (Accepted Med. Chem. Res., September 2017)

“Bioactive Seco-Lanostane-Type Triterpenoids from the Root of Leplaea mayombensis” Lazare S. Sidjui,  Kenneth O. Eyong, Kenneth G. Hull, Gabriel N. Folefoc, Valerie M. Leddet, Gaёtan Herbette, Evelyne Ollivier, Joseph Taube, Kevin Klausmeyer, and Daniel Romo (Accepted J. Nat. Prod., September 2017)

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