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The Baylor CPRIT Synthesis and Drug-Lead Discovery Laboratory will focus on the devolpment and application of chemo- and site-selective methods for the derivatization of biologically and pharmacologically important natural products and other bioactive small molecules and the high throughput optimization of synthetic transformations.

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Lab News:

New Manuscript Accepted for Publication:

“Comparison of Alicyclobacillus acidocaldarius o‑Succinylbenzoate Synthase to Its Promiscuous N‑Succinylamino Acid Racemase/o‑Succinylbenzoate Synthase Relatives” Denis Odokonyero, Andrew W. McMillan, Udupi A. Ramagopal, Rafael Toro, Dat P. Truong, Mingzhao Zhu, Mariana S. Lopez, Belema Somiari, Meghann Herman, Asma Aziz, Jeffrey B. Bonanno, Kenneth G. Hull, Stephen K. Burley, Daniel Romo, Steven C. Almo, and Margaret E. Glasner (Biochemistry 2018 Accepted ASAP)

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